Chrome, Y U No Function Again?

Google Chrome is my favorite web browser, I love its interface, simplicity, fast, and the navigation tabs. I've been using it for years since migrating from Mozilla that always pop up error message and 'application not responding'. However, Chrome sometimes has errors too - showing 'application not responding' and 'unknown plugin unresponsive: bla-bla-bla'.
My Google Chrome doesn't function nice, again! Theme I installed and bookmark I saved have been lost and back to its basic setting! I don't know what cause it so! Whether hacker, virus, or what, it sucks!